Methyl 6-Chloroindole-3-carboxylate

Methyl 6-Chloroindole-3-carboxylate - Names and Identifiers

Name	1H-Indole-3-carboxylic acid, 6-chloro-, methyl ester
Synonyms	Methyl 6-Chloroindole-3-carboxylate methyl 6-chloro-1H-indole-3-carboxylate 6-Chloro-1H-indole-3-carboxylic acid methyl ester 6-Chloro-1H-indole-3-Carbocylic acid methyl ester 1H-INDOLE-3-CARBOXYLIC ACID,6-CHLORO-,METHYL ESTER 1H-Indole-3-carboxylic acid, 6-chloro-, methyl ester
CAS	921194-97-0

Methyl 6-Chloroindole-3-carboxylate - Physico-chemical Properties

Molecular Formula	C10H8ClNO2
Molar Mass	209.63
Storage Condition	Sealed in dry,Room Temperature

Methyl 6-Chloroindole-3-carboxylate - Introduction

1H-Indole-3-carboxylic acid, 6-chlorophyll-, methyl ester is an organic compound whose chemical structure contains an indole ring and a carboxylic acid group. Its chemical formula is C10H8ClNO2.

The following is a detailed description of the nature, use, formulation and safety information of 1H-Indole-3-carboxylic acid, 6-choro-, methyl ester:

Nature:
-Appearance: 1H-Indole-3-carboxylic acid, 6-choro-, methyl ester is a white crystalline solid or powder.
-Solubility: It has good solubility in common organic solvents such as ethanol, dimethyl sulfoxide and chloroform.

Use:
-intermediate: 1H-Indole-3-carboxylic acid, 6-chloro-, methyl ester is often used as an intermediate in organic synthesis for the synthesis of various compounds.
-Drug research: It has certain applications in the field of drug research, such as for the synthesis of antibacterial drugs, anti-tumor drugs, etc.

Preparation Method:
1H-Indole-3-carboxylic acid, 6-chloro-, methyl ester can usually be synthesized by the following steps:
1. Indole reacts with acetone to form indole -3-one;
2. Indole -3-one reacts with phosphorus chloride to form 6-chloroindol-3-one;
3. 6-chloroindol-3-one reacts with methanol under the catalysis of base to generate 1H-indole-3-carboxylic acid, 6-chloro-, methyl ester.

Safety Information:
- 1H-Indole-3-carboxylic acid, 6-chloro-, methyl ester should be stored and used to avoid contact with skin, eyes and mucous membranes.
-It may be toxic to the environment, so its waste should be properly disposed of in accordance with local laws and regulations.
-In handling and handling, appropriate personal protective measures should be taken, such as wearing gloves, protective glasses, etc.

Last Update：2024-04-09 20:49:11